Airports:
Perugia - 40km - 45 minutes drive - Ryanair from Stansted.
Rome - 180km - 2.5 hours drive - All major airlines.
Ancona - 90km - 2 hours drive - Ryainair.
Pisa - 130km - 2.5 hours drive - Easyjet and Ryanair.
Bologna - 130km - 3 hours drive - Ryanair and Easyjet.
Milan - 300km - 5 hours drive - All major airlines.
Train:
Nearest station is at Trestina (10km away) with direct link to Perugia (30 minutes) which then goes to Rome (2 hours).
50 Minute drive to Arezzo with fast trains to Milan and Rome.